So many thanks for your help Don,
I install the SP 16, and check IIS, but if the IIs application pool is on Framework 2 I still have exactly the same error, if I change the IIS application pool on framework 4 i've got this message :
404 - File or directory not found.
The resource you are looking for might have been removed, had its name changed, or is temporarily unavailable.
I
On this server there is a certificate (https), is it possible it comes from this or what else ?
Eric